FORUM FOR PSYCHIATRY RESIDENTS
Would you like to react to this message? Create an account in a few clicks or log in to continue.

Follow Forum_Psych on Twitter
Search
 
 

Display results as :
 

Rechercher Advanced Search

Statistics
We have 222 registered users
The newest registered user is raheelmemon

Our users have posted a total of 1140 messages in 613 subjects
If you are seeing this, you have attempted to link to the UpToDate widget but are experiencing a problem. Please visit UpToDate for more information.
Share

Acute Mania: Comparative Efficacy & Acceptability of Pharmacological Treatment

FORUM FOR PSYCHIATRY RESIDENTS :: Psychiatry :: Psychiatry-Neurology-Psychology discussion :: Psycho-Pharmacology

Go down

Acute Mania: Comparative Efficacy & Acceptability of Pharmacological Treatment Empty Acute Mania: Comparative Efficacy & Acceptability of Pharmacological Treatment

Post  Admin Wed Aug 17, 2011 11:48 pm

Acute Mania: Comparative Efficacy & Acceptability of Pharmacological Treatment


Meta-analysis published in Lancet 17 Aug, 2011:

68 randomised controlled trials (16 073 participants) were systematically from Jan 1, 1980, to Nov 25, 2010, which compared any of the following pharmacological drugs at therapeutic dose range for the treatment of acute mania in adults: aripiprazole, asenapine, carbamazepine, valproate, gabapentin, haloperidol, lamotrigine, lithium, olanzapine, quetiapine, risperidone, topiramate, and ziprasidone.

The main outcomes were the mean change on mania rating scales and the number of patients who dropped out of the allocated treatment at 3 weeks. Analysis was done by intention to treat.

Interpretation
Haloperidol Tops the List
Overall, antipsychotic drugs were significantly more effective than mood stabilisers. Risperidone, olanzapine, and haloperidol should be considered as among the best of the available options for the treatment of manic episodes. These results should be considered in the development of clinical practice guidelines.

Read the full article here: Lancet

Acute Mania: Comparative Efficacy & Acceptability of Pharmacological Treatment Logo_lancet
Acute Mania: Comparative Efficacy & Acceptability of Pharmacological Treatment 8anxio10
Admin
Admin
Admin
Admin

Posts : 948
Points : 2102
Reputation : 0
Join date : 2011-02-19
Location : Philadelphia

https://psychiatry.forumotion.com

Back to top Go down

Back to top

FORUM FOR PSYCHIATRY RESIDENTS :: Psychiatry :: Psychiatry-Neurology-Psychology discussion :: Psycho-Pharmacology

 
Permissions in this forum:
You cannot reply to topics in this forum