Follow Forum_Psych on Twitter

Display results as :

Rechercher Advanced Search

We have 222 registered users
The newest registered user is raheelmemon

Our users have posted a total of 1140 messages in 613 subjects
If you are seeing this, you have attempted to link to the UpToDate widget but are experiencing a problem. Please visit UpToDate for more information.

Q.5 Clozapine Neutopenia

Go down

Q.5 Clozapine Neutopenia Empty Q.5 Clozapine Neutopenia

Post  Admin on Mon Jul 11, 2016 8:43 pm

Q.5 Clozapine Neutopenia Hiv_210

Q.5: Patient with treatment resistant schizophrenia is initiated on Clozapine. During routing monitoring, ANC (Absolute Neutrophil Count) was found to be 900/μL. Patient had normal ANC of >1500/μL prior to Clozapine initiation. Which of the monitoring recommendations are correct as your next step?
(a) Once a week until ANC ≥ 1500/μL.
(b) Three times weekly until ANC ≥ 1500/μL.
(c) Two times weekly until ANC ≥ 1000/μL.
(d) Daily until ANC ≥ 1000/μL.


Patient have Moderate Neutropenia (500 - 999/μL). 
ANC Monitoring for general population on clozapine with moderate neutropenia:
• Recommend hematology consultation.
• Interrupt treatment for suspected clozapine induced neutropenia.
• Resume treatment once ANC normalizes to ≥ 1000/μL
• Daily until ANC ≥ 1000/μL, then Three times weekly until ANC ≥ 1500/μL. Once ANC ≥ 1500/μL check ANC weekly for 4 weeks, then return to patient’s last “Normal Range” ANC monitoring interval.

Source: Clozapine REMS.

Q.5 Clozapine Neutopenia Images16Click on Q.5 Clozapine Neutopenia Reply_en to post your comments

Posts : 948
Points : 2102
Reputation : 0
Join date : 2011-02-19
Location : Philadelphia

Back to top Go down

Back to top

Permissions in this forum:
You cannot reply to topics in this forum