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Dose-dependent risk of malformations with antiepileptic drugs
FORUM FOR PSYCHIATRY RESIDENTS :: Psychiatry :: Psychiatry-Neurology-Psychology discussion :: Psycho-Pharmacology
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Dose-dependent risk of malformations with antiepileptic drugs
Admin Tue Jun 07, 2011 1:43 pm
Dose-dependent risk of malformations with antiepileptic drugs
Four commonly used antiepileptic drugs (Carbamazepine, Lamotrigine, Valproic acid, and Phenobarbital) are associated with a dose-dependent increased risk of major birth defects when used at the beginning of pregnancy.
"The risk of major congenital malformations is influenced not only by type of antiepileptic drug, but also by dose and other variables, which should be taken into account in the management of epilepsy in women of childbearing potential"
Details ----> Article From The Lancet Neurology
Four commonly used antiepileptic drugs (Carbamazepine, Lamotrigine, Valproic acid, and Phenobarbital) are associated with a dose-dependent increased risk of major birth defects when used at the beginning of pregnancy.
"The risk of major congenital malformations is influenced not only by type of antiepileptic drug, but also by dose and other variables, which should be taken into account in the management of epilepsy in women of childbearing potential"
Details ----> Article From The Lancet Neurology
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FORUM FOR PSYCHIATRY RESIDENTS :: Psychiatry :: Psychiatry-Neurology-Psychology discussion :: Psycho-Pharmacology
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