FORUM FOR PSYCHIATRY RESIDENTS
Would you like to react to this message? Create an account in a few clicks or log in to continue.
Follow Forum_Psych on Twitter
Search
 
 

Display results as :
 


Rechercher Advanced Search

Statistics
We have 222 registered users
The newest registered user is raheelmemon

Our users have posted a total of 1140 messages in 613 subjects
If you are seeing this, you have attempted to link to the UpToDate widget but are experiencing a problem. Please visit UpToDate for more information.
Share

Quiz: Selective Serotonin Reuptake Inhibitors

Go down

Quiz: Selective Serotonin Reuptake Inhibitors Empty Quiz: Selective Serotonin Reuptake Inhibitors

Post  Admin Sun Jun 30, 2013 8:10 pm


Q: Which of the following statement regarding SSRI (Selective serotonin reuptake inhibitors) is FALSE?

(a) Fluoxetine has shown positive benefit in bulimic patients but failed to show any benefit in prevention of relapse in anorexic patients.
(b) Among SSRIs, only Fluoxetine and Sertraline have pharmacologically active metabolites.
(c) Among cytochrome P450 enzymes, 2D6 is most important in drug interactions with most SSRIs.
(d) SSRIs do not have long acting formulations (taken weekly or biweekly)
(e) Sertraline have more linear dose response curve, whereas others have relatively flat dose response curve.

Quiz: Selective Serotonin Reuptake Inhibitors Ssri-s10
Admin
Admin
Admin
Admin

Posts : 948
Points : 2102
Reputation : 0
Join date : 2011-02-19
Location : Philadelphia

https://psychiatry.forumotion.com

Back to top Go down

Quiz: Selective Serotonin Reuptake Inhibitors Empty Re: Quiz: Selective Serotonin Reuptake Inhibitors

Post  Admin Mon Jul 01, 2013 8:08 pm

Admin wrote:
Q: Which of the following statement regarding SSRI (Selective serotonin reuptake inhibitors) is FALSE?

(a) Fluoxetine has shown positive benefit in bulimic patients but failed to show any benefit in prevention of relapse in anorexic patients.
(b) Among SSRIs, only Fluoxetine and Sertraline have pharmacologically active metabolites.
(c) Among cytochrome P450 enzymes, 2D6 is most important in drug interactions with most SSRIs.
(d) SSRIs do not have long acting formulations (taken weekly or biweekly)
(e) Sertraline have more linear dose response curve, whereas others have relatively flat dose response curve.

Answer:
(b) and (d) are wrong statements above.

Fluoxetine has been shown to have a positive effect on the binge-purge cycle in some bulimic patients. The largest controlled study to date of fluoxetine in the prevention of relapse in anorexic patients failed to show any benefit for fluoxetine in preventing relapse relative to placebo
Source: Walsh et al. JAMA 295(22):2605–2612, 2006.

Among SSRIs: Fluoxetine (norfluoxetine with half life of 7–14 days), Sertraline (N-desmethylsertraline with half life of 2–3 days) and Escitalopram (S-demethylcitalopram) have pharmacologically active metabolites.

Among cytochrome P450 enzymes, 2D6 is most important in drug interactions with most SSRIs.

Long acting formulations of SSRIs: Fluoxetine (90mg once weekly), Paroxetine CR & FLuvoxamine CR.

Sertraline have more linear dose response curve, whereas others have relatively flat dose response curve
Admin
Admin
Admin
Admin

Posts : 948
Points : 2102
Reputation : 0
Join date : 2011-02-19
Location : Philadelphia

https://psychiatry.forumotion.com

Back to top Go down

Back to top

- Similar topics

 
Permissions in this forum:
You cannot reply to topics in this forum