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Q. Which Benzodiazepines Have Least Potential for Drug Interactions?

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FORUM FOR PSYCHIATRY RESIDENTS :: Psychiatry :: Psychiatry-Neurology-Psychology discussion :: Psycho-Pharmacology

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Q. Which Benzodiazepines Have Least Potential for Drug Interactions? Empty Q. Which Benzodiazepines Have Least Potential for Drug Interactions?

Post  Admin Wed Jun 13, 2012 8:13 pm

Confuse
Q. Which Benzodiazepines Have Least Potential for Drug Interactions?

(a) Alprazolam
(b) Lorazepam
(c) Diazepam
(d) Flurazepam


Last edited by Admin on Wed May 28, 2014 7:49 pm; edited 1 time in total
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Post  P450 Mon Jun 18, 2012 8:05 pm

B. Lorazepam - metabolized through glucuronidation , which is less susceptible to drug interactions

Alprazolam - 3A4 metabolized: much potential for drug interactions
Diazepam - mainly 2C19 metabolized: still some potential for drug interactions
Flurazepam - multiple cyp enzymes: less potential

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Q. Which Benzodiazepines Have Least Potential for Drug Interactions? Empty Re: Q. Which Benzodiazepines Have Least Potential for Drug Interactions?

Post  Admin Mon Jun 18, 2012 8:25 pm

Correct.

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