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New Genetic Studies Point to One Origin of Depression

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New Genetic Studies Point to One Origin of Depression

Post  Admin on Wed Aug 03, 2011 6:51 pm

Two new genetic studies hint at the location of a gene that may be involved in the origin of depression.

Study 1 (Hamilton et al):
Study finds an evidence for genetic linkage between major depressive disorder and the same region on chromosome 3. The linked region contains the gene GRM7, which encodes a protein for the metabotropic glutamate receptor 7 (mGluR7). The significance of this finding remains uncertain, although it points to a gene that might hold significant promise for further developments in studying the pathophysiology and treatment of major depressive disorder.
Read here for details:
AJP-Hamilton et al

Study 2 (Pergadia et al):
The authors tested for genetic linkage of DSM-IV-diagnosed major depressive disorder in families that were ascertained for cigarette smoking. Genome-wide significant linkage was detected for major depressive disorder on chromosome 3p in a sample ascertained for smoking.
Read here for more details:
AJP- Pergadia et al

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