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Combining L-Methylfolate With Antidepressant Shows Significant Boost In Patient Response
FORUM FOR PSYCHIATRY RESIDENTS :: Psychiatry :: Psychiatry-Neurology-Psychology discussion :: Psychiatry In Depth
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Combining L-Methylfolate With Antidepressant Shows Significant Boost In Patient Response
Admin Tue Jun 14, 2011 9:27 am
Combining L-Methylfolate With Antidepressant Shows Significant Boost In Patient Response
New findings from a multi-center, randomized, placebo-controlled clinical study of Deplin® 15mg (L-methylfolate) added to commonly prescribed antidepressants known as selective serotonin reuptake inhibitors (SSRIs) showed that all patients who achieved remission at 30 days using Deplin® 15mg adjuvant therapy, and who chose to enter a 12 month maintenance phase, maintained their remission after a year of treatment.
"In patients with inadequate response to SSRI monotherapy for depression, the addition of L-methylfolate 15mg (Deplin®) may offer a personalized approach to improve responses to antidepressant therapy in genetic errors of folate metabolism such as the MTHFR polymorphism," said Dr Zajecka. "Although this study is speculative, it represents promise in a genotypically defined subgroup of patients and an option for personalized medicine in major depression."
Click here for more details about this study: Deplin + SSRI
New findings from a multi-center, randomized, placebo-controlled clinical study of Deplin® 15mg (L-methylfolate) added to commonly prescribed antidepressants known as selective serotonin reuptake inhibitors (SSRIs) showed that all patients who achieved remission at 30 days using Deplin® 15mg adjuvant therapy, and who chose to enter a 12 month maintenance phase, maintained their remission after a year of treatment.
"In patients with inadequate response to SSRI monotherapy for depression, the addition of L-methylfolate 15mg (Deplin®) may offer a personalized approach to improve responses to antidepressant therapy in genetic errors of folate metabolism such as the MTHFR polymorphism," said Dr Zajecka. "Although this study is speculative, it represents promise in a genotypically defined subgroup of patients and an option for personalized medicine in major depression."
Click here for more details about this study: Deplin + SSRI
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FORUM FOR PSYCHIATRY RESIDENTS :: Psychiatry :: Psychiatry-Neurology-Psychology discussion :: Psychiatry In Depth
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